| CYP isoenzymes | |||||
| CYP19 1 subfamily, 1 gene
(steroid biosynthesis NB oestrogen) | |||||
| Isoenzyme | Substrates | Inducer | Inhibitor | Alleles | Effects (alleles, interactions) |
| CYP19 | (aromatase: aromatises A ring of steroid nucleus =
androgen to oestrogen!)
also in human temporal lobe | ? PgE2 | vorozole, letrozole, anastrozole (all non-steroidal) ; exemestane (steroid) | ? | (present in placenta)
A1 allele may predispose to breast cancer |
| Last update 2000-1-22 | Author jo@anaesthetist.com |