CYP isoenzymes
CYP19 1 subfamily, 1 gene
(steroid biosynthesis NB oestrogen)
Isoenzyme Substrates Inducer Inhibitor Alleles Effects (alleles, interactions)
CYP19 (aromatase: aromatises A ring of steroid nucleus = androgen to oestrogen!)
also in human temporal lobe
? PgE2 vorozole, letrozole, anastrozole (all non-steroidal) ; exemestane (steroid) ? (present in placenta)
A1 allele may predispose to breast cancer

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Last update 2000-1-22 Author