Cytochrome P450 : Alphabetical drug list
Quick Links:
1A2 2C9 2C19 2D6 2E1 3A4
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X, Y, Z
Drug CYP interaction Clinical consequences
yohimbine ? 2D6 : metabolism ?
zafirlukast 2C9 : INHIBITS
(and metabolism)
? interaction with eg. warfarin
3A4 : inhibits 3A4 interactions (?)
zanamivir minimal CYP interaction nil (?)
zidovudine ? (interaction of this or other nucleoside analogues, and other anti-retrovirals such as protease inhibitors is NOT likely) [Clin Pharmacokinet 1999 Apr;36(4):289-304]
zileuton 1A2 : metabolism
(also 2C9, 3A4 [Hayes] )
interaction with theophyllin, {? also propranolol, warfarin}
zolmitriptan CYP1A2 : metabolism [Xenobiotica 1999 Aug;29(8):847-57] ?
zonisamide 3A4,5 : metabolism (also 2C19) potential for interaction with 3A4/5 inhibitors [Eur J Clin Pharmacol 1998 Apr;54(2):177-83] eg. ketoconazole, cyclosporin A and miconazole
zotepine 3A4 {also 1A2, 2D6} : metabolism ?
zuclopenthixol CYP2D6 : metabolism ?

Quick Links:
1A2 2C9 2C19 2D6 2E1 3A4

Page author: jo@anaesthetist.com Last update: 2000-6-22