|
CYP isoenzymes
++ = mitochondrial # = found in lung tissue | |||||
| CYP51 1 subfamily, 1 gene, 2 pseudogenes
(lanosterol 14-alpha demethylase) | |||||
| Isoenzyme | Substrates | Inducer | Inhibitor | Alleles | Effects (alleles, interactions) |
| CYP51
{Marked evolutionary conservation!} | lanosterol (makes cholesterol) | ? | ketoconazole, itraconazole; oxysterols | ? | (human CYP51 may be partially inhibited by azole antifungals) |
| Last update 2000-1-22 | Author jo@anaesthetist.com |