CYP isoenzymes
++ = mitochondrial
CYP27 2 subfamilies
(bile acid biosynthesis; vitamin D 1-alpha hydroxylase);
Isoenzyme Substrates Inducer Inhibitor Alleles Effects (alleles, interactions)
CYP27A1++ (sterol 27-hydroxylase) See also CYP7A, CYP8B
Also 25-hydroxylates vitamin D !
? ? ? (cerebrotendinous xanthomatosis)
{A challenging problem to clone this gene!}
(1-alpha hydroxylates vitamin D)

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Last update 2000-1-22 Author