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Cytochrome P450 : Alphabetical drug list J K |
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| J,K | ||
| Drug | CYP interaction | Clinical consequences |
| ketoconazole :
See also azole antifungals | CYP51 : INHIBITS | ? |
| CYP17 : inhibits 17 alpha hydroxylase in adrenals. | 'adrenal suppression' (with other enzymes) | |
| CYP3A4 : metabolism | ? | |
| 2C19 : INHIBITS | ? | |
| 3A4 : INHIBITS (IC50 = 0.01 to 0.04 µM) | See reference for itraconazole | |
| 2A6 : INHIBITS | ? | |
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| Page author: jo@anaesthetist.com | Last update: 2000-6-22 |